Metabolic characterization of the natural progression of chronic hepatitis B.

Genome Med · 2016 · PMC4902991 · PMID 27286979

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an increasing trendno p-value reported

Both clusters showed an increasing trend across the four clinical phases of chronic HBV infection, with their defining difference observed when taking the HCs into account.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.