Comparative evaluation of dexmedetomidine and midazolam-ketamine combination as sedative agents in pediatric dentistry: A double-blinded randomized controlled trial.

In the present study, combination of oral midazolam–ketamine (83.3%) resulted in better behavior than intranasal dexmedetomidine (61.6%) during the treatment, and both were better than control group (0%) though the results were statistically insignificant between midazolam–ketamine and dexmedetomidine ( P = 0.460), the results were highly significant in relation to control group.

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