Comprehensive RNA Analysis of the NF1 Gene in Classically Affected NF1 Affected Individuals Meeting NIH Criteria has High Sensitivity and Mutation Negative Testing is Reassuring in Isolated Cases With Pigmentary Features Only.

EBioMedicine · 2016 · PMC4909377 · PMID 27322474

Europe PMC DOI

hedged sentences

0.0070

closest p · 0.1× alpha

0.0800

boldest claim

The sentences

highly significantp = 0.007actually significant

The presence of DNET in 2/13 (15%) negative screens versus 2/348 (0.6%-Relative Risk of 0.004) with mutations is highly significant ( p = 0.007).

also in 132,142 other papers

did not quite reach significancep = 0.08so close (0.05 < p ≤ 0.1)

Whole gene deletions were present in 6/166 (3.6%) of familial samples with identified mutations and 15/182 (8.2%) of sporadic samples but this difference did not quite reach significance ( p = 0.08).

also in 350 other papers

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