Selenophene and thiophene-core estrogen receptor ligands that inhibit motility and development of parasitic stages of Haemonchus contortus.

In particular, Haemonchus contortus (the barber’s pole worm) is a highly significant pathogen of livestock worldwide, affecting hundreds of millions of small ruminants (including sheep and goats) and causing economic losses [ 1 , 2 ] estimated at tens of billions of dollars per annum.

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