a statistical trendp=0.23
While 2uM of sorafenib alone didn't affect viability, the addition of Metformin resulted in statistically significant reduction in viability of SK-Hep-1 (p=0.029), and a statistical trend in reduction of viability in PLC/PRF/5 and HuH-7 (p=0.23, p=0.059 respectively; Fig. 1 ).