Postoperative Pain and Intravenous Patient-Controlled Analgesia-Related Adverse Effects in Young and Elderly Patients: A Retrospective Analysis of 10,575 Patients.

4 , 28 , 30 , 32 , 36 , 40 Sex-based differences with respect to the development of PONV may be attributed to variations in serum gonadotropin or other hormone levels, and thus these differences may not be significant in preadolescent age groups or in patients older than 80 years. 32 – 35 In our results, the female sex in even elderly patients was an independent risk factor for rescue antiemetic requirement, while its OR (OR: 1.56) was relatively lower than that of young patients (OR: 1.76).

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