borderline significantP = 0.05
The meta-analysis of the comparison of the means of three studies that compared NHD patients with a follow up period of 4–6 months with control patients that continued on CHD for 4–6 months showed a borderline significant increase in serum albumin in NHD patients (mean difference 1.3 g/l, 95% CI 0.02; 2.58, P = 0.05) ( Fig 2b ).