biosigner: A New Method for the Discovery of Significant Molecular Signatures from Omics Data.

The two features were highly significant by hypothesis testing of difference between type medians ( p < 10 −7 and p < 10 −6 , respectively; Figure 4D ), and to a lesser extent by testing of correlation with age ( p < 10 −4 and p < 10 −3 ) or body mass index ( p < 10 −2 and p < 5 × 10 −2 ).

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