Barely Significant
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Penicillin-Binding Protein Transpeptidase Signatures for Tracking and Predicting β-Lactam Resistance Levels in Streptococcus pneumoniae.

mBio · 2016 · PMC4916381 · PMID 27302760

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The sentences

highly significantP < 1 × 10 −15actually significant
The differences in median PEN MICs were highly significant ( P < 1 × 10 −15 for all pair-wise comparisons by Mann-Whitney U test).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.