Barely Significant
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Genetic influences on nicotinic α5 receptor (CHRNA5) CpG methylation and mRNA expression in brain and adipose tissue.

Genes Environ · 2015 · PMC4917931 · PMID 27350810

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1
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0.0510
closest p · 1.0× alpha
0.0510
boldest claim

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a trend towards significancep =0.051so close (0.05 < p ≤ 0.1)
In the MuTHER dataset, the linear model for methylation at cg22563815 (Expression ~ cg22563815*bisulfite conversion concentration*bisulfite conversion efficiency*rs7164030) showed a trend towards significance ( t =−1.95, p =0.051, β=−2.34; Fig. 4c ), while methylation at cg17108064 (Expression ~ cg17108064*batch*bisulfite conversion efficiency*rs7164030) did not predict expression ( t =1.48, p =0.14, β=0.99; Fig. 4d ).

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