Barely Significant
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Cultivation of Staphylococcus epidermidis in the Human Spaceflight Environment Leads to Alterations in the Frequency and Spectrum of Spontaneous Rifampicin-Resistance Mutations in the rpoB Gene.

Front Microbiol · 2016 · PMC4923109 · PMID 27446039

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highly significantno p-value reported
epidermidis exhibited a 24-fold higher frequency of mutation to Rif R than did GC cultures, and this difference was found to be highly significant ( Figure 2B ).

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