Surveillance of HIV Transmitted Drug Resistance in Latin America and the Caribbean: A Systematic Review and Meta-Analysis.

PLoS One · 2016 · PMC4927069 · PMID 27355626

Europe PMC DOI

hedged sentences

0.0001

closest p · 0.0× alpha

0.0200

boldest claim

The sentences

an increasing trendp<0.0001actually significant

An increasing trend was observed for overall TDR when comparing 2000–2005 (6.0%) and 2006–2015 (8.2%) (p<0.0001), which was associated with significant NNRTI TDR increase (p<0.0001).

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a decreasing trendp = 0.02actually significant

Interestingly, a decreasing trend in NRTI TDR was also observed in LAC (4.7% vs. 3.8%, p = 0.02), possibly reflecting previous exposure to mono- or dual therapy and the consequent introduction of more potent ART schemes.

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