Our ITC results demonstrate that phosphorylation of Ser670 can enhance the binding by ~11 fold, and phosphorylation of Ser676 can also strengthen the binding by ~4 fold, while Thr680 phosphorylation may not be significant.
← all excerpts
Crystal structure of a PP2A B56-BubR1 complex and its implications for PP2A substrate recruitment and localization.
1
—
—