Nevertheless, it is noteworthy that IC 50 values from rhodamine 123 assay showed highly significant correlation with those from the digoxin assay [ 41 ] ( Figure 4 ), indicating that the two methods similarly ranked the P-gp inhibitors according to their inhibitory potential. 3.5.
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Evaluation of P-Glycoprotein Inhibitory Potential Using a Rhodamine 123 Accumulation Assay.
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