An Optimal Bahadur-Efficient Method in Detection of Sparse Signals with Applications to Pathway Analysis in Sequencing Association Studies.

PLoS One · 2016 · PMC4933358 · PMID 27380176

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may not be significantno p-value reported

As a result, signals may not be significant in the "single marker-single trait" analysis, but many such values from related genes might provide valuable information regarding gene function and regulation.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.