Mitochondrial-targeted catalase is good for the old mouse proteome, but not for the young: 'reverse' antagonistic pleiotropy?

All treatment groups showed a highly significant degree of correlation with OWT in all ten top pathways combined, and this correlation remained significant for every individual pathway in YWT and YmCAT (Fig. 3 B,D) as well as eight of ten of the pathways in OmCAT (Fig. 3 C).

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