The association ALS-FTD seemed to express higher atrophy ratings compared to ALS patients for the motor cortex, anterior cingulate, temporal and occipital lobes and a statistical trend for the orbitofrontal cortex. 34 , 35 DTI shows reduced white matter integrity relative in frontal and temporal regions when comparing to healthy older adults.
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Frontotemporal Dementia in Amyotrophic Lateral Sclerosis: From Rarity to Reality?
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