demonstrated the presence of CTCs to be a highly significant and independent prognostic factor for OS and DFS with multivariate hazard ratios of 2.18 for OS and 2.11 for DFS [ 20 ].
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Detection of circulating tumor cells using manually performed immunocytochemistry (MICC) does not correlate with outcome in patients with early breast cancer - Results of the German SUCCESS-A- trial.
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