Multiplex enhancer-reporter assays uncover unsophisticated TP53 enhancer logic.

When looking at the subsets created independently for each method, we see a highly significant overlap, with 190 of 231 CHEQ-seq positives being labeled as positives or grayzone in STARR-seq (82.3%, χ 2 P -value = 1.24 × 10 −26 ) ( Fig. 2 B,C).

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