borderline significancep = 0.06
The overall estimate of effect size for conversion to THR favored the cell therapy group, although it reached only borderline significance levels (OR = 0.30, 95% CI: 0.08–1.06; p = 0.06) in the presence of a moderate degree of statistical heterogeneity (Q-test = 4.39, df = 3, p = 0.22, and I 2 = 32%), ( Figure 6B , see Supplementary data).