Barely Significant
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Human islets contain four distinct subtypes of β cells.

Nat Commun · 2016 · PMC4942571 · PMID 27399229

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highly significantno p-value reported
Given the inter-individual heterogeneity inherent to human clinical specimens, these differences are highly significant and likely represent only a minimal estimate of the true transcriptome heterogeneity.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.