Resolving Discrepant Findings on ANGPTL8 in β-Cell Proliferation: A Collaborative Approach to Resolving the Betatrophin Controversy.

We extended our proliferation analysis to include total pancreatic proliferation and found that ANGPTL8 significantly increased extra-islet cell proliferation, compared to MBP alone as measured by EdU, with a weak trend (p = 0.11) towards increased proliferation by Ki67 ( Fig 6J and 6K , S8 Table ).

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