Association between aberrant APC promoter methylation and breast cancer pathogenesis: a meta-analysis of 35 observational studies.

PeerJ · 2016 · PMC4950556 · PMID 27478702

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an increasing trendno p-value reported

The accuracy of NAF mainly relies on the experience of the cytopathologist which may result in an increasing trend for false negatives ( Jeronimo et al. , 2003 ).

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highly significantno p-value reported

The corrected OR was still highly significant for the association between APC methylation and BC risk (OR = 1.444, 95% CI [1.081–1.965]), further proving the stability of our meta-analysis.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.