Hypomethylation and Genetic Instability in Monosomy Blastocysts May Contribute to Decreased Implantation Potential.

PLoS One · 2016 · PMC4951028 · PMID 27434648

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ADM2 , PACSIN2 , PARVB , and PIWIL3 are located within highly significant hypo-methylated cytogenic regions of chromosome 22 and were all found to have significantly lower expression in monosomy 22 blastocysts compared to controls.

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