Subgroup analyses according to ethnicity showing marginally significant association between this single nucleotide polymorphism and HCC risk indicate that G870A may be significantly associated with HCC risk in Caucasian populations (recessive model: AA vs GG + AG: OR =2.34, 95% CI =1.60–3.42, P <0.0001; dominant model: AG + AA vs GG: OR =2.44, 95% CI =1.19–4.97, P =0.01; homozygous model: AA vs GG: OR =3.42, 95% CI =1.80–6.50, P =0.0002; allelic model: A vs G: OR =2.06, 95% CI =1.31–3.24, P =0.002), but not in Asian populations.
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Association between cyclin D1 G870A polymorphism and hepatocellular carcinoma risk: a meta-analysis.
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