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Is real world evidence influencing practice? A systematic review of CPRD research in NICE guidances.

BMC Health Serv Res · 2016 · PMC4960862 · PMID 27456701

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an increasing trendno p-value reported
However, there seems to be an increasing trend in the use of healthcare system data to inform clinical practice, especially as the real world validity of clinical trials is being questioned.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.