A Catalogue of Altered Salivary Proteins Secondary to Invasive Ductal Carcinoma: A Novel In Vivo Paradigm to Assess Breast Cancer Progression.

The signaling events mediated by HDAC Class III was highly significant at the p < 0.01 × 10 −16 level as was the glucocorticoid receptor regulatory network at the p < 0.01 × 10 −6 level.

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This coupled with the up-regulated activities of the IFN-γ/Stat1 pathway and the increase concentrations of TNF-α and IFN-γ may be significant as this suggests possible T cell exhaustion from constant exposure to tumor antigens or the absence of the HLA-A2 allele 44 45 46 47 .

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