Human brown adipose tissue [(15)O]O2 PET imaging in the presence and absence of cold stimulus.

There was a positive trend of increase in MRO 2 in the pectoralis major (RT: 0.05 ± 0.04 versus cold: 0.4 ± 0.5 mL/100 g/min, p = 0.06) and splenius cervicis muscles (RT: 0.2 ± 0.2, cold: 0.4 ± 0.3 mL/100 g/min, p = 0.15) while there was no difference in MRO 2 in the deltoid muscle (0.1 ± 0.1 versus 0.2 ± 0.2 mL/100 g/min, p = 0.60, RT vs. cold, respectively), trapezius muscle (0.1 ± 0.1 versus 0.2 ± 0.3 mL/100 g/min, p = 0.29) or neck subcutaneous white adipose tissue (0.5 ± 0.1 versus 0.5 ± 0.1 mL/100 g/min, p = 0.48, RT vs. cold, respectively, Fig. 4a ).

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