The Microbiome of Aseptically Collected Human Breast Tissue in Benign and Malignant Disease.

Beta diversity analysis reveals a highly significant difference in community membership between the breast and skin tissue microbiota, as indicated by unweighted UniFrac analysis (MiRKAT P < 1e-4, Fig. 2E ), but the difference is not significant in weighted analysis (MiRKAT P = 0.14, Fig. 2F ), indicating that the major difference lies in the rare or less abundant lineages 22 .

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In addition, likely due to greater power from the slightly larger sample size, weighted UniFrac analysis also showed marginally significant differences.

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