The total activity, calculated by the number of total arm entries in the Y-maze test, was not significantly changed among the eight groups despite a decreasing trend in the aged groups, indicating that exploratory activity was not remarkably affected by genotype and aging [ Figure 3a ].
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Amyloid β Protein Aggravates Neuronal Senescence and Cognitive Deficits in 5XFAD Mouse Model of Alzheimer's Disease.
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