The regulation of GATA3 expression is considered essentially significant, because its downregulation allows the production of Tbx21 which is mainly stimulated by Th1-related cytokines, like IL-12 and interferon-γ (IFN-γ) [ 5 , 6 ].
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The leishmanicidal activity of oleuropein is selectively regulated through inflammation- and oxidative stress-related genes.
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