A Genome-Wide Association Study for Regulators of Micronucleus Formation in Mice.

Interestingly, after correcting for the effect of potential confounding variables (see Materials and Methods ), we found small but highly significant positive correlations between micronucleus level and several hematological measures; the red blood cells distribution width (RDW, P = 2.55 × 10 −26 , Spearman R 2 = 0.1), the hemoglobin concentration distribution width (HDW, P = 1.63 × 10 −12 , R 2 = 0.04, Spearman), the mean cellular hemoglobin concentration (CHCM, P = 3.14 × 10 −11 , R 2 = 0.04, Spearman), and the measure of blood hemoglobin (measHGB, P = 1.88 × 10 −6 , R 2 = 0.02, Spearman).

also in 82,756 other papers