Autophagy mediated by arginine depletion activation of the nutrient sensor GCN2 contributes to interferon-γ-induced malignant transformation of primary bovine mammary epithelial cells.

Cell Death Discov · 2016 · PMC4979444 · PMID 27551491

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a decreasing trendno p-value reported

Western blot analysis showed that SQSTM1/p62 expression exhibited a decreasing trend in both a time- and dose-dependent manner ( Figures 3b and c ), suggesting that IFN- γ triggers a complete autophagic flux in BMECs.

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