Antibody-Dependent NK Cell Activation Is Associated with Late Kidney Allograft Dysfunction and the Complement-Independent Alloreactive Potential of Donor-Specific Antibodies.

The variables identified as significantly associated with outcome variables ( p < 0.05), that were marginally significant ( p < 0.20, t ) in the univariate analysis, or that are considered clinically relevant were selected for inclusion in the Cox regression model, which analyzed parameters associated with a loss in kidney graft function equal to at least 10% of the eGFR over the follow-up period of the 148 patients (median duration of follow-up: 13.3 months, 25–75th percentile: 12.1–15.1 months post-evaluation).

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