Barely Significant
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Network-Informed Gene Ranking Tackles Genetic Heterogeneity in Exome-Sequencing Studies of Monogenic Disease.

Hum Mutat · 2015 · PMC4982032 · PMID 26394720

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hedged sentence
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closest p · 0.0× alpha
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boldest claim

The sentences

highly significantP < 10 −4actually significant
Using a degree‐constrained method of permutation to test the null ( H 0 ) versus alternative hypothesis ( H 1 ) of whether the number and degree distribution of disease‐causing genes account for the number of disease subnetworks, in each case the observed number of disease subnetworks is highly significant ( P < 10 −4 ; Supp.

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