borderline significantP = 0.056
When absolute CD8 count was replaced by changes in CD8 from pre-cART values (Table 3 [ii]), the increase in CD8 was borderline significant in the univariate model (HR = 1.18, 95% CI = 1.00–1.40; P = 0.056), but was not associated with VF in the adjusted model (HR = 1.01, 95% CI = 0.84–1.22; P = 0.909). 4.