In another prospective study, LINE-1 hypomethylation was associated with breast cancer risk ( Deroo et al , 2014 ), whereas two others found marginally significant associations between LINE-1 hypermethylation, and kidney ( Karami et al , 2015 ) and bladder cancer ( Andreotti et al , 2014 ).
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Prospective changes in global DNA methylation and cancer incidence and mortality.
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