Are lower levels of red blood cell transfusion more cost-effective than liberal levels after cardiac surgery? Findings from the TITRe2 randomised controlled trial.

However, analyses of a secondary outcome, mortality at 90 days, found a borderline significant difference between the groups (4.2% of patients in the restrictive group died vs 2.6% of patients in the liberal group, p=0.045) creating uncertainty about recommending restrictive transfusion after cardiac surgery.

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