Phenotypic Characterization of Toxic Compound Effects on Liver Spheroids Derived from iPSC Using Confocal Imaging and Three-Dimensional Image Analysis.

Assay Drug Dev Technol · 2016 · PMC5003004 · PMID 27494736

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a possible trendno p-value reported

However, 21 of the 33 compounds with detectable effects in both 3D and 2D formats yielded slightly lower IC 50 values for the 3D cultures, suggesting a possible trend toward stronger toxicity effects in 3D culture.

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