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Interstitial Perfusion Culture with Specific Soluble Factors Inhibits Type I Collagen Production from Human Osteoarthritic Chondrocytes in Clinical-Grade Collagen Sponges.

PLoS One · 2016 · PMC5008682 · PMID 27584727

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a positive trendno p-value reported
The densitometric analysis of WB data confirmed a significantly lower production of type I collagen and showed a positive trend for type II/type I collagen ratio in sponges cultured in dynamic conditions ( Fig 6b ).

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