According to the two-way repeated-measures ANOVA, the effect of treatment (antibodies against TNFR1, TNFR2, or control IgG) (DF = 6; F = 5.06; P < 0.001) and time (day 4, 7, or 14) (DF = 2; F = 44.00; P < 0.001) were highly significant.
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Cerebral ischemia-induced angiogenesis is dependent on tumor necrosis factor receptor 1-mediated upregulation of α5β1 and αVβ3 integrins.
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