marginally significantP > 0.057
Lines L1, L2, L4, and L5 showed marginally significant increases in fitness ( t -test of log W against zero: 0.134 > P > 0.057), whereas L3 showed a more marked increase ( W = 6.22; P = 0.002) but still less pronounced than in pkr −/− cells ( Fig. 1 C).