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Compared to Intermittant Claudication Critical Limb Ischemia Is Associated with Elevated Levels of Cytokines.

PLoS One · 2016 · PMC5017674 · PMID 27611073

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a decreasing trendno p-value reported
Only PDGF showed a decreasing trend toward CLI when the three groups were compared with each other.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.