The Poly-cistronic miR-23-27-24 Complexes Target Endothelial Cell Junctions: Differential Functional and Molecular Effects of miR-23a and miR-23b.

A gene set enrichment analysis (GSEA) revealed that many of the predicted targets (see Supplementary Table S1 ) are involved in the adherens junctions pathway ( P = 9.67 e −18 ) with a highly significant False Discovery Rate q -values of 8.01 e −16 .

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A slight trend to increase thrombin-induced permeability was seen in some experiments but was not consistent using mimic 23b transfected cells ( Figure 4d ).

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