Genome-wide measures of DNA methylation in peripheral blood and the risk of urothelial cell carcinoma: a prospective nested case-control study.

Br J Cancer · 2016 · PMC5023776 · PMID 27490804

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a decreasing trendno p-value reported

Although the associations between DNA methylation levels and risk of UCC did not appear to vary substantially by genomic region, there was a trend of decreasing risk of invasive UCC in non-regulatory regions, and a decreasing trend of superficial UCC in regulatory regions.

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