C1Q Assay Results in Complement-Dependent Cytotoxicity Crossmatch Negative Renal Transplant Candidates with Donor-Specific Antibodies: High Specificity but Low Sensitivity When Predicting Flow Crossmatch.

J Transplant · 2016 · PMC5027038 · PMID 27688904

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highly significantno p-value reported

The story dates back to 1969, when Patel and Terasaki demonstrated for the first time the highly significant correlation between a positive complement-dependent cytotoxicity (CDC) crossmatch (XM) assay and hyperacute or accelerated acute graft rejection in kidney transplant recipients [ 1 ].

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