Quadratic model type was selected to be the proper model that fit the CCD of cholesterol oxidase production by Streptomyces cavourensis strain NEAE-42, where the results of fit summary showed that, the quadratic model is a highly significant with a very low probability value [( P model > F ) < 0.0001].
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Identification and statistical optimization of fermentation conditions for a newly isolated extracellular cholesterol oxidase-producing Streptomyces cavourensis strain NEAE-42.
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