Genomic landscape of DNA repair genes in cancer.

Oncotarget · 2016 · PMC5029628 · PMID 27004405

Europe PMC DOI

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highly significantno p-value reported

Despite the uncertainty of whether all defects in the DNA damage response play a central role in cancer pathogenesis, they are highly significant in disease progression and treatment.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.