MACC1 overexpression was the only factor among biomarkers (KRAS, BRAF, MMR, osteopontin, SASH1) in a panel associated (to a highly significant degree) with distant metastases, thus serving as an independent predictor for formation of metachronous metastasis [ 39 ].
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The potential therapeutic applications and prognostic significance of metastasis-associated in colon cancer-1 (MACC1) in cancers.
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