Are sites with multiple single nucleotide variants in cancer genomes a consequence of drivers, hypermutable sites or sequencing errors?

1 )—the difference is highly significant using the Chi-square goodness of fit test ( p < 0.0001) for both the whole genome (Total) and when separating the genome into non-coding transposable elements (TE), non-coding non-transposable elements and (NTE) and exons (EX) ( Table 1A ).

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